Could a Parent's nose bacteria fix a Child's microbiome after antibiotics?
NCT ID NCT06805994
First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This early study tests whether transferring nasal bacteria from a parent to a child can restore the child's nasal microbiome after they have been treated with antibiotics for staph bacteria. The study involves 175 children who have had staph in their nose and recently finished antibiotic treatment. Researchers will measure changes in the child's nasal bacteria after the transplant to see if it helps restore diversity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nasal microbiota transplant (NMT)
- What this could lead to
- If it works, this could point toward a way to restore healthy nasal bacteria in children after antibiotic treatment, potentially reducing staph infections.
- What could go wrong
- This is a very early Phase 1 study, so it is not yet known if the transplant is safe or effective. The main goal is just to measure changes in nasal bacteria, not to treat disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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