Could a Parent's nose bacteria fix a Child's microbiome after antibiotics?

NCT ID NCT06805994

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tests whether transferring nasal bacteria from a parent to a child can restore the child's nasal microbiome after they have been treated with antibiotics for staph bacteria. The study involves 175 children who have had staph in their nose and recently finished antibiotic treatment. Researchers will measure changes in the child's nasal bacteria after the transplant to see if it helps restore diversity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nasal microbiota transplant (NMT)

What this could lead to

If it works, this could point toward a way to restore healthy nasal bacteria in children after antibiotic treatment, potentially reducing staph infections.

What could go wrong

This is a very early Phase 1 study, so it is not yet known if the transplant is safe or effective. The main goal is just to measure changes in nasal bacteria, not to treat disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infectious disease staphylococcal infection staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••