New drug aims to shield autoimmune patients from Life-Threatening infections

NCT ID NCT07220915

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 6 times

Summary

This study tests whether a medicine called Panzyga can prevent major infections in people with autoimmune or rheumatic conditions who have low antibody levels after receiving B-cell depletion therapy. About 360 adults will receive either Panzyga or a placebo, and researchers will track how many develop serious infections. The goal is to see if Panzyga can safely reduce infection risk in this vulnerable group.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital of Lithuanian University of Health Sciences (LSMU) Kauno klinikos

    ACTIVE_NOT_RECRUITING

    Kaunas, 50161, Lithuania

  • Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji

    ACTIVE_NOT_RECRUITING

    Warsaw, 02-637, Poland

  • P. Stradins Clinical University Hospital

    ACTIVE_NOT_RECRUITING

    Riga, 1002, Latvia

  • Perseverance Research Center, Phoenix Neurological Associates

    RECRUITING

    Scottsdale, Arizona, 85253, United States

  • Riga East Clinical University Hospital

    ACTIVE_NOT_RECRUITING

    Riga, 1079, Latvia

  • UMHAT Sveti Georgi EAD

    ACTIVE_NOT_RECRUITING

    Plovdiv, 4002, Bulgaria

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Other studies related to the condition(s) this trial covers.