New drug combo targets tough cancers in groundbreaking trial

NCT ID NCT06922591

Summary

This study is testing whether a new oral drug called TNG462 is safe and effective when combined with other cancer drugs for people with advanced pancreatic or non-small cell lung cancer. The trial will involve about 183 adults whose cancers have specific genetic changes (MTAP loss and sometimes a RAS mutation). Researchers aim to find the best dose and see if these drug combinations can shrink tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

  • Mayo Clinic Cancer Center

    RECRUITING

    Rochester, Minnesota, 55905-0001, United States

    Contact

  • Mayo Clinic Jacksonville

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact

  • Mayo Clinic Scottsdale

    RECRUITING

    Scottsdale, Arizona, 85259-5452, United States

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 11065, United States

    Contact

  • NEXT Dallas

    RECRUITING

    Irving, Texas, 74039, United States

    Contact

  • NEXT Oncology

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact

  • Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68124, United States

    Contact

  • Sarah Cannon Research Institute Denver

    RECRUITING

    Denver, Colorado, 80218, United States

    Contact

  • University of Indiana

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

Conditions

Explore the condition pages connected to this study.