Triple punch against pancreatic cancer: chemo, immunotherapy, and radiation before surgery

NCT ID NCT06384560

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new approach for people with pancreatic cancer that can be surgically removed. Before surgery, patients receive a combination of chemotherapy (mFOLFIRINOX), an immunotherapy drug (pembrolizumab), and targeted radiation (SABR). After surgery, they continue with chemotherapy and immunotherapy. The goal is to see if this triple treatment helps patients live longer without the cancer coming back. The trial is for adults with early-stage or borderline resectable pancreatic cancer who are healthy enough to undergo these treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam University Medical Center

    RECRUITING

    Amsterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erasmus University Medical Center

    RECRUITING

    Rotterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maastricht University Medical Center

    NOT_YET_RECRUITING

    Maastricht, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Antonius Ziekenhuis

    RECRUITING

    Nieuwegein, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••