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Timing of chemo may boost survival in pancreatic cancer

NCT ID NCT04927780

Ongoing Disease control Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving chemotherapy both before and after surgery helps people with pancreatic cancer live longer compared to chemotherapy only after surgery. About 378 patients with resectable pancreatic cancer will be randomly assigned to one of two treatment schedules. The goal is to see if the combined approach improves overall survival.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER PANCREATIC DUCTAL ADENOCARCINOMA RESECTABLE PANCREATIC ADENOCARCINOMA

Contacts and locations

Locations

  • Amphia Hospital

    Breda, Netherlands

  • Amsterdam UMC

    Amsterdam, Netherlands

  • Catharina Hospital

    Eindhoven, Netherlands

  • Deventer Hospital

    Deventer, Netherlands

  • Erasmus MC University Medical Center

    Rotterdam, Netherlands

  • Isala Hospital

    Zwolle, Netherlands

  • Jeroen Bosch Hospital

    's-Hertogenbosch, Netherlands

  • Karolinska University Hospital

    Stockholm, Sweden

  • Leiden University Medical Center

    Leiden, Netherlands

  • Maasstad Ziekenhuis

    Rotterdam, Netherlands

  • Maastricht UMC+

    Maastricht, Netherlands

  • Meander Medical Center

    Amersfoort, Netherlands

  • Medical Center Leeuwarden

    Leeuwarden, Netherlands

  • Medisch Spectrum Twente

    Enschede, Netherlands

  • OLVG

    Amsterdam, Netherlands

  • Radboud University Medical Center

    Nijmegen, Netherlands

  • Regional Academic Center Utrecht, Antonius Hospital

    Utrecht, Netherlands

  • Sahlgrenska University Hospital

    Gothenburg, Sweden

  • Skåne University Hospital

    Lund, Sweden

  • Tjongerschans Hospital

    Heerenveen, Netherlands

  • University Medical Center Groningen

    Groningen, Netherlands

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