New hope for tough pancreatic cancer: personalized drug cocktail enters trials

NCT ID NCT06483555

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a low dose of erlotinib to standard chemotherapy (gemcitabine and nab-paclitaxel) is safe and effective for people with advanced pancreatic cancer. Participants are grouped by tumor type: those with 'basal-like' tumors get the new combo, while those with 'classical' tumors receive standard care. The trial aims to improve survival and control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gemcitabine, nab-paclitaxel, and erlotinib

What this could lead to

If successful, this could lead to a more effective treatment for people with a specific type of pancreatic cancer (basal-like) that is often harder to treat.

What could go wrong

This is an early-phase trial (Phase I/II) with a small number of participants, so results may not apply to everyone. Adding erlotinib may increase side effects without improving outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

basal cell neoplasm malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••