New hope for diabetic nerve pain: platform trial tests multiple treatments

NCT ID NCT05476276

Completed Symptom relief Sponsor: James P. Rathmell, MD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested several experimental treatments for painful diabetic peripheral neuropathy, a common complication of diabetes that causes burning or shooting pain in the feet and hands. 127 adults with this condition rated their daily pain on a 0-10 scale to see if the treatments helped. The goal was to find safer and more effective options for managing this chronic pain.

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Conditions

The condition(s) this trial relates to.

diabetic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAINFUL DIABETIC NEUROPATHY

Contacts and locations

Locations

Clinical Inquest Center

Beavercreek, Ohio, 45431, United States
Columbia University Medical Center/Neurological Institute

New York, New York, 10032, United States
Eastern Virginia Medical School

Norfolk, Virginia, 23510, United States
Healthcare Research Network (Flossmoor)

Flossmoor, Illinois, 60422, United States
Healthcare Research Network (Hazelwood)

Hazelwood, Missouri, 63042, United States
Johns Hopkins University School of Medicine

Baltimore, Maryland, 21205, United States
Low Country Pain Center

Orangeburg, South Carolina, 29118, United States
MGH Department of Anesthesia, Critical Care, and Pain

Boston, Massachusetts, 02114, United States
Mount Sinai School of Medicine

New York, New York, 10451, United States
Nerve and Muscle Center of Texas

Houston, Texas, 77030, United States
Northwestern Department of Neurology

Chicago, Illinois, 60611, United States
SIMEDHealth LLC

Gainesville, Florida, 32607, United States
South Lake Pain Institute

Clermont, Florida, 34711, United States
University of California, San Diego

San Diego, California, 92037, United States
University of Florida

Gainesville, Florida, 32611, United States
University of Kansas Medical Center

Kansas City, Kansas, 66160, United States
University of Maryland - Baltimore

Baltimore, Maryland, 21201, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15206, United States
University of Rochester

Rochester, New York, 14627, United States
University of Utah School of Medicine

Salt Lake City, Utah, 84132, United States
University of Washington

Seattle, Washington, 32611, United States
University of Wisconsin

Madison, Wisconsin, 53706, United States
VCU Department of Neurology

Richmond, Virginia, 23298, United States

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