Electric pulses in the spine may ease diabetic nerve pain
NCT ID NCT03228420
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This trial compares a spinal cord stimulation device (HF10 therapy) plus standard medical care against standard care alone for people with long-term, hard-to-treat leg pain caused by diabetic neuropathy. About 430 adults with stable pain levels and no major neurological changes are being randomly assigned to one of the two groups. The main goal is to see if more people in the stimulation group achieve at least a 50% reduction in pain without developing new nerve problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a device that delivers 10 kHz spinal cord stimulation (HF10 therapy)
- What this could lead to
- If successful, this could offer a new, non-drug option for people with painful diabetic neuropathy who do not get enough relief from standard treatments.
- What could go wrong
- This is a post-market study, so the device is already approved, but it may not work for everyone and carries surgical risks like infection or lead migration.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Pain Management
Greenfield, Wisconsin, 53221, United States
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Coastal Orthopedics
Bradenton, Florida, 34209, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Georgia Pain Care
Stockbridge, Georgia, 30281, United States
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