Could a tiny dose of naltrexone ease diabetic nerve pain without opioids?
NCT ID NCT04678895
First seen May 12, 2026 · Last updated May 12, 2026
Summary
This study tests whether low-dose naltrexone (LDN) can safely reduce pain from diabetic neuropathy, a common complication of diabetes. About 35 adults with painful diabetic neuropathy who haven't found relief from standard treatments will receive LDN and a placebo in random order. The goal is to see if LDN, which boosts the body's natural pain relief and reduces inflammation, can be a non-opioid alternative to improve quality of life.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dartmouth-Hitchcock Medical Center
RECRUITINGLebanon, New Hampshire, 03766, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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