New study aims to ease chronic pain in opioid recovery patients

NCT ID NCT06367387

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two approaches to help people with opioid use disorder and chronic pain feel better. One is a pain self-management program with coaching and peer support. The other allows flexible dosing of buprenorphine based on pain levels. 268 adults from participating clinics will take part over 12 weeks, with follow-up surveys for a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

buprenorphine (also known as Suboxone, Subutex, Zubsolv)

What this could lead to

If successful, this could offer a better way to manage chronic pain in people being treated for opioid addiction, potentially improving their quality of life and treatment retention.

What could go wrong

This is a Phase 4 study with 268 participants, so results may not apply to everyone. Risks include psychological distress from discussing pain and possible side effects from higher buprenorphine doses.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center

    Baltimore, Maryland, 21223, United States

  • Central City Concern (CCC)

    Portland, Oregon, 97209, United States

  • MATClinics

    Dundalk, Maryland, 21222, United States

  • OHSU Harm Reduction Bridges to Care (HRBR)

    Portland, Oregon, 97239, United States

  • OHSU Internal Medicine Clinic (IMC)

    Portland, Oregon, 97239, United States

  • Recovery Works Northwest (RWNW)

    Portland, Oregon, 97233, United States

  • UPMC Internal Medicine Recovery Engagement Program (IM-REP)

    Pittsburgh, Pennsylvania, 15219, United States

  • UPMC Latterman Family Health Center

    McKeesport, Pennsylvania, 15132, United States

  • UPMC Magee-Womens Pregnancy and Women's Recovery Center (PWRC)

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC St. Margaret Family Health Center

    New Kensington, Pennsylvania, 15068, United States

  • WVU Chestnut Ridge Comprehensive Addiction Treatment Program (COAT)

    Morgantown, West Virginia, 26505, United States

  • WVU Crisis Support & Recovery Center

    Martinsburg, West Virginia, 25401, United States

  • Wells House

    Hagerstown, Maryland, 21740, United States