New study aims to ease chronic pain in opioid recovery patients

NCT ID NCT06367387

Ongoing Symptom relief Sponsor: Erin Winstanley Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two approaches to help people with opioid use disorder and chronic pain feel better. One is a pain self-management program with coaching and peer support. The other allows flexible dosing of buprenorphine based on pain levels. 268 adults from participating clinics will take part over 12 weeks, with follow-up surveys for a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buprenorphine (also known as Suboxone, Subutex, Zubsolv)
What this could lead to: If successful, this could offer a better way to manage chronic pain in people being treated for opioid addiction, potentially improving their quality of life and treatment retention.
What could go wrong: This is a Phase 4 study with 268 participants, so results may not apply to everyone. Risks include psychological distress from discussing pain and possible side effects from higher buprenorphine doses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN OPIOID-USE DISORDER

Contacts and locations

Locations

Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center

Baltimore, Maryland, 21223, United States
Central City Concern (CCC)

Portland, Oregon, 97209, United States
MATClinics

Dundalk, Maryland, 21222, United States
OHSU Harm Reduction Bridges to Care (HRBR)

Portland, Oregon, 97239, United States
OHSU Internal Medicine Clinic (IMC)

Portland, Oregon, 97239, United States
Recovery Works Northwest (RWNW)

Portland, Oregon, 97233, United States
UPMC Internal Medicine Recovery Engagement Program (IM-REP)

Pittsburgh, Pennsylvania, 15219, United States
UPMC Latterman Family Health Center

McKeesport, Pennsylvania, 15132, United States
UPMC Magee-Womens Pregnancy and Women's Recovery Center (PWRC)

Pittsburgh, Pennsylvania, 15213, United States
UPMC St. Margaret Family Health Center

New Kensington, Pennsylvania, 15068, United States
WVU Chestnut Ridge Comprehensive Addiction Treatment Program (COAT)

Morgantown, West Virginia, 26505, United States
WVU Crisis Support & Recovery Center

Martinsburg, West Virginia, 25401, United States
Wells House

Hagerstown, Maryland, 21740, United States

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