New study seeks to reduce sedation for children with broken wrists

NCT ID NCT07120763

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two lighter pain control methods for children aged 3 to 17 who need a wrist fracture reduction. One method uses a numbing injection (hematoma block) with a low dose of ketamine, and the other uses the same block with fentanyl nasal spray. These are compared to the standard full sedation with ketamine. The goal is to see if these alternatives control pain just as well while avoiding deep sedation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ketamine, Lidocaine, Fentanyl
What this could lead to
If successful, this could provide safer, less sedating pain control options for children with wrist fractures, reducing the need for full sedation.
What could go wrong
This is a small, early-phase trial with only 50 participants, so results may not apply to all children. The alternative methods may not control pain as well as full sedation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oshei Children's Hospital

    RECRUITING

    Buffalo, New York, 14203, United States

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