Nerve block may cut opioid use for cancer pain

NCT ID NCT07211386

Recruiting now Symptom relief Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a nerve block called the erector spinae plane block can reduce abdominal pain in people with gastrointestinal cancer. Researchers will compare opioid use and hospital stay length between 25 patients who get the block and a matched group who received standard care. The goal is to see if this procedure can offer effective pain relief with fewer opioids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: erector spinae plane block (a nerve block procedure)
What this could lead to: If it works, this could offer a non-opioid option for managing severe abdominal pain in people with gastrointestinal cancer.
What could go wrong: This is a small, early study with only 25 participants, so results may not apply to everyone. The nerve block may not provide enough pain relief for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia digestive system cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL MALIGNANCY PAIN CONTROL

Contacts and locations

Locations

Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Hospital of the University of Pennsylvania -- Cedar Avenue
RECRUITING

Philadelphia, Pennsylvania, 19143, United States
Penn Presbyterian Medical Center
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Pennsylvania Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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