New balloon coated with drug aims to keep leg arteries open longer

NCT ID NCT06832631

Ongoing Disease control Sponsor: OrbusNeich Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study follows 284 people with blocked leg arteries (peripheral arterial disease) who are treated with a paclitaxel-coated balloon. The balloon is inflated inside the artery to open it and release a drug that helps prevent it from narrowing again. Researchers are tracking safety and how well the artery stays open over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paclitaxel-coated balloon
What this could lead to: If successful, this could confirm that the paclitaxel-coated balloon is a safe and effective way to open blocked leg arteries and reduce the need for repeat procedures.
What could go wrong: This is an observational registry, not a randomized trial, so results may be less definitive. The drug coating may carry risks like inflammation or late complications, and long-term benefits are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease peripheral arterial occlusive disease 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE PERIPHERAL ARTERIAL OCCLUSIVE DISEASE

Contacts and locations

Locations

AZ Groennge

Kortrijk, 3000, Belgium
AZ Jan Portaels

Vilvoorde, 1800, Belgium
AZ Sint-Blasius

Dendermonde, 9200, Belgium
AZORG

Aalst, 9300, Belgium
Complejo Hospitalario Universitario de Ourense

Ourense, 32005, Spain
Hospital General de Granollers

Granollers, 08402, Spain
Hospital Universitario de Cabueñes

Gijón, 33394, Spain
Hospital Universitario de Toledo

Toledo, 45007, Spain
Klinikum Lippe Detmold

Detmold, 32756, Germany
RZ Heilig Hart Tienen

Tienen, 3300, Belgium
SRH Klinikum Karlsbad-Langensteinbach GmbH

Karlsbad, 76307, Germany
Singapore General Hospital

Singapore, 169608, Singapore
ZOL Genk

Genk, 3600, Belgium

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