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Ozonated oil: a new edge for elite athletes?

NCT ID NCT07801924

Symptom relief Sponsor: Universita degli Studi di Genova Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

Researchers are testing whether daily ozonated oil supplements can improve aerobic capacity, maximal strength, and muscular endurance in elite rugby players over six months. The oil has anti-inflammatory and antioxidant properties, but its effect on performance is unclear. Participants take the supplement alongside their regular training, and researchers measure changes in fitness and injury rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ozonated oil (O3ZONE Sport) taken daily as an oral supplement
What this could lead to
If it works, ozonated oil could become a simple supplement to help athletes improve endurance and strength while reducing injury risk.
What could go wrong
This is a small early trial with only 33 participants, so results may not apply broadly. The supplement's anti-inflammatory effects might not translate into measurable performance gains.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

33 people

The number who actually took part.

Started

Sep 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion criteria were age ≥18 Exclusion Criteria: * NA

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscular Recovery methods Strength endurance

Contacts and locations

Locations

  • Stadio del Rugby

    Avezzano, AQ, 67051, Italy

  • University of Genova

    Genova, Genova, 16132, Italy

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