Caffeine and vitamin c may fight mental fatigue to improve strength — a trial puts the combo to the test

NCT ID NCT07726745

Not yet recruiting Symptom relief Sponsor: Yunliang Zhang Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial investigates whether caffeine, vitamin C, or their combination can improve maximum strength and strength endurance in female adolescents experiencing mild mental fatigue. Forty healthy college students will complete strength tests after a mental fatigue task, with each participant trying all supplement conditions in a random order. The study aims to see if these common substances can counteract the physical effects of mental tiredness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: caffeine and vitamin C
What this could lead to: If effective, a simple combination of caffeine and vitamin C could help counteract mental fatigue and improve physical performance in young athletes.
What could go wrong: This is a small, early-stage trial in healthy female college students, so results may not apply to other groups. Caffeine can cause side effects like jitters or sleep disruption.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAXIMUM FORCE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Mental Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAXIMUM FORCE MENTAL FATIGUE STRENGTH ENDURANCE

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.