New hope for kids with MS: Head-to-Head trial of two daily pills

NCT ID NCT06408259

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 35 times

Summary

This study compares two daily pills, ozanimod and fingolimod, in children and adolescents aged 10 to 17 with relapsing-remitting multiple sclerosis (RRMS). The goal is to see which drug better prevents relapses and controls brain lesions seen on MRI. Participants will be randomly assigned to one of the two treatments and monitored for about two years. Both drugs are already approved for adults with MS, so this trial aims to find the best option for younger patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • 2Ca Braga

    RECRUITING

    Braga, 4710-243, Portugal

    Contact Phone: •••-•••-••••

  • CHUVI- Hospital Alvaro Cunqueiro

    RECRUITING

    Vigo, Pontevedra [Pontevedra], 36203, Spain

    Contact Phone: •••-•••-••••

  • Centro Hospitalar de Lisboa Central

    RECRUITING

    Lisbon, 1169-050, Portugal

    Contact Phone: •••-•••-••••

  • Hospital Universitari i Politecnic La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact

  • Hospital Universitario Miguel Servet

    RECRUITING

    Zaragoza, 50009, Spain

    Contact

  • Hospital Universitario Virgen Macarena

    RECRUITING

    Seville, 41009, Spain

    Contact Phone: •••-•••-••••

  • Local Institution - 0078

    WITHDRAWN

    Mexico City, DIF, 04530, Mexico

  • Local Institution - 0081

    NOT_YET_RECRUITING

    Milan, Lombardy, 20133, Italy

    Contact

  • Local Institution - 0091

    WITHDRAWN

    Cincinnati, Ohio, 45229, United States

  • Local Institution - 0092

    NOT_YET_RECRUITING

    Portland, Oregon, 97225, United States

    Contact

  • Local Institution - 0093

    WITHDRAWN

    Chicago, Illinois, 60611, United States

  • Local Institution - 0096

    NOT_YET_RECRUITING

    Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

    Contact

  • Local Institution - 0102

    WITHDRAWN

    Porto, 4200-319, Portugal

  • Local Institution - 0114

    NOT_YET_RECRUITING

    Loma Linda, California, 92354, United States

    Contact

  • Local Institution - 0131

    NOT_YET_RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact

  • Local Institution - 0132

    WITHDRAWN

    Teaneck, New Jersey, 07666, United States

  • Local Institution - 0133

    NOT_YET_RECRUITING

    El Paso, Texas, 79912, United States

    Contact

  • Local Institution - 0134

    NOT_YET_RECRUITING

    Caguas, 00725, Puerto Rico

    Contact

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-••••

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

    Contact Phone: •••-•••-••••

  • Neurological Center Of Latium

    RECRUITING

    Rome, Roma, 00178, Italy

    Contact Phone: •••-•••-••••

  • Ondokuz Mayıs Universitesi

    RECRUITING

    Samsun, 55270, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Ospedale San Raffaele

    RECRUITING

    Milan, Lombardy, 20132, Italy

    Contact Phone: •••-•••-••••

  • Prof. Dr. Alexandru Obregia Psychiatry Hospital

    RECRUITING

    Bucharest, Bucharest, 041914, Romania

    Contact Phone: •••-•••-••••

  • Royal Children's Hospital

    RECRUITING

    Melbourne, Victoria, 3052, Australia

    Contact Phone: •••-•••-••••

  • Spitalul Clinic de Copii Doctor Victor Gomoiu

    RECRUITING

    Bucharest, Bucharest, 022102, Romania

    Contact Phone: •••-•••-••••

  • Unidade Local de Saúde de Coimbra, E.P.E.

    RECRUITING

    Coimbra, 3000-602, Portugal

    Contact Phone: •••-•••-••••

  • University of California Davis Health

    RECRUITING

    Sacramento, California, 95817, United States

    Contact Phone: •••-•••-••••

  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-••••

  • University of Louisville, Norton Children's Research Institute

    RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact Phone: •••-•••-••••

  • University of Naples Federico II

    RECRUITING

    Naples, Campania, 80131, Italy

    Contact Phone: •••-•••-••••

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-••••

  • Uniwersytecki Szpital Kliniczny w Poznaniu

    RECRUITING

    Poznan, Greater Poland Voivodeship, 60-355, Poland

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.