New hope for kids with MS: Head-to-Head drug trial launches
NCT ID NCT06408259
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two daily pills, ozanimod and fingolimod, to see which works better at preventing MS relapses in children and teens aged 10 to 17. Participants will be randomly assigned to one of the two drugs and monitored for about two years. The goal is to find a more effective and safer option for managing this chronic condition.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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2Ca Braga
RECRUITINGBraga, 4710-243, Portugal
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CHUVI- Hospital Alvaro Cunqueiro
RECRUITINGVigo, Pontevedra [Pontevedra], 36203, Spain
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Centro Hospitalar de Lisboa Central
RECRUITINGLisbon, 1169-050, Portugal
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Hospital Universitari i Politecnic La Fe
RECRUITINGValencia, 46026, Spain
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Hospital Universitario Miguel Servet
RECRUITINGZaragoza, 50009, Spain
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Hospital Universitario Virgen Macarena
RECRUITINGSeville, 41009, Spain
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Local Institution - 0078
WITHDRAWNMexico City, DIF, 04530, Mexico
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Local Institution - 0081
NOT_YET_RECRUITINGMilan, Lombardy, 20133, Italy
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Local Institution - 0091
WITHDRAWNCincinnati, Ohio, 45229, United States
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Local Institution - 0092
NOT_YET_RECRUITINGPortland, Oregon, 97225, United States
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Local Institution - 0093
WITHDRAWNChicago, Illinois, 60611, United States
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Local Institution - 0096
NOT_YET_RECRUITINGEsplugues de Llobregat, Barcelona [Barcelona], 08950, Spain
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Local Institution - 0102
WITHDRAWNPorto, 4200-319, Portugal
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Local Institution - 0114
NOT_YET_RECRUITINGLoma Linda, California, 92354, United States
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Local Institution - 0131
NOT_YET_RECRUITINGNew Brunswick, New Jersey, 08901, United States
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Local Institution - 0132
WITHDRAWNTeaneck, New Jersey, 07666, United States
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Local Institution - 0133
NOT_YET_RECRUITINGEl Paso, Texas, 79912, United States
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Local Institution - 0134
NOT_YET_RECRUITINGCaguas, 00725, Puerto Rico
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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National Taiwan University Hospital
RECRUITINGTaipei, 10002, Taiwan
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Neurological Center Of Latium
RECRUITINGRome, Roma, 00178, Italy
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Ondokuz Mayıs Universitesi
RECRUITINGSamsun, 55270, Turkey (Türkiye)
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Ospedale San Raffaele
RECRUITINGMilan, Lombardy, 20132, Italy
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Prof. Dr. Alexandru Obregia Psychiatry Hospital
RECRUITINGBucharest, Bucharest, 041914, Romania
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Royal Children's Hospital
RECRUITINGMelbourne, Victoria, 3052, Australia
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Spitalul Clinic de Copii Doctor Victor Gomoiu
RECRUITINGBucharest, Bucharest, 022102, Romania
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Unidade Local de Saúde de Coimbra, E.P.E.
RECRUITINGCoimbra, 3000-602, Portugal
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University of California Davis Health
RECRUITINGSacramento, California, 95817, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Louisville, Norton Children's Research Institute
RECRUITINGLouisville, Kentucky, 40202, United States
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University of Naples Federico II
RECRUITINGNaples, Campania, 80131, Italy
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University of South Florida
RECRUITINGTampa, Florida, 33612, United States
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Uniwersytecki Szpital Kliniczny w Poznaniu
RECRUITINGPoznan, Greater Poland Voivodeship, 60-355, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gentle electric zap to the brain restore memory in MS?
- Brain scans may reveal how MS drug affects mental fatigue
- Brain scans could reveal which MS drugs fight mental exhaustion
- Brain shrinkage as a crystal ball for MS progression?
- Can a Once-a-Month shot tame MS relapses?
- Can MS treatments protect the mind as well as the body?