New balloon coated with drug could keep airways open longer
NCT ID NCT07191860
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a special balloon coated with the drug paclitaxel to treat benign (non-cancerous) narrowing of the windpipe or main breathing tubes. The balloon is inflated to open the airway, and the drug may help keep it open longer. About 200 adults with this condition will be randomly assigned to get either the drug-coated balloon or a standard uncoated balloon. The goal is to see if the drug-coated balloon reduces the need for repeat procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- paclitaxel-coated balloon
- What this could lead to
- If it works, this could reduce how often patients need repeat procedures to open a narrowed airway, improving their quality of life.
- What could go wrong
- This is a relatively early-stage trial with 200 participants. The drug-coated balloon may not work better than standard treatment, and there are risks like bleeding, airway injury, or breathing problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21218, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can 3D-printed stents solve complex airway blockages?
- Custom 3D stents aim to make breathing easier and safer
- Laser vs. balloon: which works best for narrowed windpipe?
- Microwave probe aims to clear cancer-blocked airways, but study halted early
- Scientists probe healing after windpipe surgery
- New balloon could keep blocked airways open longer