New device aims to prevent clots in stroke patients

NCT ID NCT06477016

Ongoing Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new device called OsciPulse that rapidly compresses the calves to improve blood flow and reduce the risk of blood clots in people hospitalized after a stroke. About 40 adults with leg weakness will be randomly assigned to receive either OsciPulse or standard compression therapy. The main goal is to see if OsciPulse lowers a blood-clot marker called D-dimer more than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OsciPulse device (non-invasive leg compression)
What this could lead to: If it works, this could offer a better way to prevent dangerous blood clots in stroke patients who cannot move their legs.
What could go wrong: This is a very small pilot study with only 40 people, so results may not apply widely. The device may be no better than standard compression or may be uncomfortable for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE

Contacts and locations

Locations

HUP Neurology Dept. of Stroke and Neurocritical Care- University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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