Monthly capsule may keep wheezing away in babies at risk
NCT ID NCT02148796
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a monthly oral bacterial extract (Broncho-Vaxom) could prevent wheezing lower respiratory tract infections in infants aged 6-18 months who are at high risk for asthma. Over 800 participants received either the extract or a placebo for 10 days each month over two years. The goal was to see if the treatment could delay the first wheezing episode during a three-year follow-up period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Broncho-Vaxom (bacterial extract)
What this could lead to
If it works, this could lead to a simple monthly treatment to prevent wheezing and asthma in high-risk infants.
What could go wrong
This is a Phase 2 trial, so results are still early. The treatment may not prove effective in larger or longer studies, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Children's Hospital, Harvard University
Boston, Massachusetts, 02115, United States
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Children's National Health System
Washington D.C., District of Columbia, 20037, United States
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Cincinnati Children's Hospital & Medical Center
Cincinnati, Ohio, 45229, United States
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Columbia University
New York, New York, 10032, United States
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Emory University
Atlanta, Georgia, 30322, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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University of Arizona
Tucson, Arizona, 85724, United States
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University of California San Francisco, Benioff Children's Hospital
Oakland, California, 94609, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Wisconsin
Madison, Wisconsin, 53792-4108, United States
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Washington University
St Louis, Missouri, 63110, United States