Math model aims to perfect thyroid drug doses for kids
NCT ID NCT06864351
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study tests a computer model called OptiThyDose that helps doctors find the best dose of thyroid medication for children with congenital hypothyroidism or Graves' disease. The model uses past lab results to keep thyroid hormone levels in a healthy range. About 150 children will take part, and half will get doses guided by the model to see if it improves control compared to standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levothyroxine (LT4) or carbimazole/methimazole (CMZ/MMZ)
What this could lead to
If it works, this could help doctors give children with thyroid disease a more precise drug dose, improving symptom control and reducing the need for frequent blood tests.
What could go wrong
This is an early-stage study with only 150 children, so the model may not work for everyone. It also relies on existing drugs, not a new treatment, so the benefit may be modest.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Paediatric Endocrinology, Diabetology and Gynaecology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris
NOT_YET_RECRUITINGParis, 75015, France
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Paediatric Endocrinology and Diabetology, University Children's Hospital Basel (UKBB)
RECRUITINGBasel, Canton of Basel-City, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact