Pregnancy and opioids: new study aims to predict risks for mom and baby

NCT ID NCT03923374

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 600 pregnant women who are taking buprenorphine for opioid use disorder. Researchers will collect genetic samples, perform MRIs, and track health outcomes to better understand why some mothers and babies have complications. The goal is to improve treatment and reduce the severity of neonatal abstinence syndrome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

buprenorphine

What this could lead to

If successful, this research could help doctors identify which mothers and babies are at higher risk for poor outcomes, leading to better, personalized care during pregnancy.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may take years to translate into clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Children's Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact