Can Opioid-Free anesthesia improve surgery recovery?
NCT ID NCT06476600
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This trial tests whether avoiding opioids during anesthesia leads to better recovery after gallbladder surgery. Half of the participants receive standard opioid-based anesthesia, while the other half receive an opioid-free approach using dexmedetomidine. The study measures recovery quality using a patient questionnaire and tracks heart rate and blood pressure during surgery. It includes adults aged 18-65 with low surgical risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dexmedetomidine and Nalbuphine
- What this could lead to
- If successful, this could show that opioid-free anesthesia provides similar or better recovery without the risks of opioids.
- What could go wrong
- This is a small, early-phase trial with only 42 participants, so results may not apply broadly. Dexmedetomidine can cause side effects like low heart rate or blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LAPAROSCOPIC CHOLECYSTECTOMY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Dow university hospital, Dow university of health sciences
Karachi, Sindh, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Simple breathing exercises after gallbladder surgery may cut pain and nausea
- Which ventilation mode breathes better during laparoscopic surgery?
- Which airway device works best for laparoscopic gallbladder surgery? a Head-to-Head trial
- Which Add-On drug eases pain after gallbladder surgery? a Head-to-Head test
- Drug combo may banish post-surgery fatigue in gallbladder patients
- Heart-Rate monitor could make anesthesia safer and faster