Scientists probe why some opioid users struggle more: new study looks at mind, body, and society

NCT ID NCT06021548

Ongoing Knowledge-focused Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to understand why some people with opioid use disorder have more severe addiction than others. Researchers will collect blood, saliva, and hair samples from 350 participants and combine that with detailed interviews about their social and mental health. The goal is to find biological markers that, together with life experiences, could better predict how the disease progresses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better ways to measure opioid addiction severity and predict its course, helping tailor treatments.
What could go wrong: This is an observational study, not testing a treatment. It may not directly improve patient outcomes, and results may not apply to all opioid users.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Centre d'étude des mouvements sociaux (CEMS) UMR8044/INSERM U1276 - École des Hautes Etudes en Sciences Sociales (EHESS)

Paris, 75006, France
Service Universitaire d'Addictologie, Hospices Civils de Lyon

Bron, 69678, France
Service d'Addictologie, Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

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