Can we skip the opioids after wrist surgery? new study tests safer pain control

NCT ID NCT05215236

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using only non-opiate pain medications works as well as standard opiates after wrist fracture repair surgery. Seventy-two adults who had surgery for a broken wrist were randomly assigned to receive either non-opiate pain relievers or opiate-based painkillers. Researchers measured how much pain medication patients used and their pain levels to see if the opiate-sparing approach could effectively manage pain while reducing opioid use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-opiate pain medications

What this could lead to

If successful, this could show that non-opiate pain control works as well as opiates after wrist surgery, potentially reducing opioid prescriptions.

What could go wrong

This is a small, completed trial with only 72 participants, so results may not apply to everyone. Pain relief might be less effective without opiates for some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

radius fracture Wrist Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Campbell Clinic

    Germantown, Tennessee, 38138, United States