New radiation approach aims to cut treatment time and side effects for breast cancer
NCT ID NCT03077841
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a shorter, more focused radiation treatment (hypofractionated partial breast irradiation) for women with early-stage breast cancer. The goal is to see if targeting only the tumor site can reduce side effects and improve cosmetic outcomes compared to standard whole-breast radiation. About 928 participants who had breast-conserving surgery are being studied, but the trial is currently suspended.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hypofractionated partial breast irradiation (radiation therapy)
- What this could lead to
- If successful, this could offer a shorter, more convenient radiation treatment with fewer side effects for women with early-stage breast cancer.
- What could go wrong
- The trial is currently suspended, and it is a phase II/III study, so results are not yet confirmed. The approach may not be as effective or safe as standard whole-breast radiation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baptist MD Anderson Cancer Center
Jacksonville, Florida, 32207, United States
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Community Cancer Center East
Indianapolis, Indiana, 46219, United States
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Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
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Covenant Medical Center Harrison
Saginaw, Michigan, 48602, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson Cancer Center at Cooper-Voorhees
Voorhees Township, New Jersey, 08043, United States
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MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson West Houston
Houston, Texas, 77079, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
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MD Anderson in The Woodlands
Conroe, Texas, 77384, United States
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OhioHealth Mansfield Hospital
Mansfield, Ohio, 44903, United States
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Piedmont Hospital
Atlanta, Georgia, 30309, United States
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Presbyterian Hospital
Albuquerque, New Mexico, 87106, United States
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Saint Luke's Baptist Health System
San Antonio, Texas, 78229, United States
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Summit Medical Group
Berkeley Heights, New Jersey, 07922, United States
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