New lupus pill ONTO1 enters early human testing

NCT ID NCT07107659

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 28 times

Summary

This early-phase study tests whether a new drug, ONTO1, is safe and tolerable for people with lupus nephritis or systemic lupus erythematosus (SLE). Researchers will give ONTO1 alongside standard lupus treatments to 61 adults and look for side effects and signs of symptom improvement. The goal is to find the safest dose and gather initial evidence for larger future trials.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.