Could some breast cancer patients skip surgery? new trial investigates

NCT ID NCT07357948

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether women with triple-negative breast cancer who have a complete response to chemo-immunotherapy can safely skip breast and lymph node surgery. Half of the 150 participants will receive standard care including surgery, while the other half will have no surgery. The goal is to see if avoiding surgery leads to similar cancer control with fewer side effects and better quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omission of surgery

What this could lead to

If successful, this could allow some women with triple-negative breast cancer to avoid surgery after chemo-immunotherapy, reducing complications and improving quality of life while maintaining cancer control.

What could go wrong

This is a phase 2 trial with only 150 participants, so results are preliminary. Skipping surgery might increase the risk of cancer returning in the breast or lymph nodes, and the approach may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Georges-François Leclerc

    Dijon, 21000, France

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  • Hôpital Tenon

    Paris, 75020, France

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  • Institut Curie Saint-Cloud

    Saint-Cloud, 92210, France

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  • Institut Curie-Paris

    Paris, 75005, France

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