Fish oil Face-Off: EPA vs. DHA for better heart health

NCT ID NCT06494488

Recruiting now Knowledge-focused Sponsor: The Miriam Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study is testing two types of fish oil—EPA and DHA—to see how they affect blood clotting and cholesterol in people with high triglycerides. Eighty participants will take one of the two oils for a month and have their blood tested. The goal is to learn which oil might be better for heart health, but it's too early to draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fish oil (eicosapentaenoic acid and docosahexaenoic acid)
What this could lead to: If successful, this could help clarify which type of fish oil is better for heart health in people with high cholesterol.
What could go wrong: This is a very early, small study (80 people) that only looks at blood markers, not actual heart attacks or strokes. Results may not lead to clear treatment changes.

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Conditions

The condition(s) this trial relates to.

hypertriglyceridemia inherited lipid metabolism disorder Lipid Metabolism Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTRIGLYCERIDEMIA LIPID METABOLISM DISORDERS

Contacts and locations

Locations

Brown University Health - Lipid Clinic
RECRUITING

Providence, Rhode Island, 02914, United States

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