New study checks if cancer drug olutasidenib changes how other medicines work

NCT ID NCT07486713

Recruiting now Knowledge-focused Sponsor: Rigel Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study looks at how the cancer drug olutasidenib affects the way the body processes other medications. Researchers will give 16 adults with IDH1-mutated cancers a mix of test drugs before and during olutasidenib treatment to measure changes in drug levels. The goal is to ensure safe and effective dosing when olutasidenib is used alongside other medicines.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Olutasidenib
What this could lead to: If successful, this study could help doctors understand how olutasidenib interacts with other medications, leading to safer treatment plans for patients with IDH1-mutated cancers.
What could go wrong: This is a small, early-phase drug interaction study, not designed to test whether olutasidenib works against cancer. Results may not apply to all patients or predict real-world outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AML (ACUTE MYELOID LEUKEMIA) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute myeloid leukemia cancer cholangiocarcinoma glioma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AML (ACUTE MYELOID LEUKEMIA) CHOLANGIOCARCINOMA GLIOMA SOLID TUMOR MALIGNANCIES

Contacts and locations

Locations

New York Presbyterian Hospital-Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
UCI Irvine Health
RECRUITING

Orange, California, 92868, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.