Targeted pill trial offers hope for advanced breast cancer patients with genetic flaws
NCT ID NCT03344965
Summary
This study is testing whether the drug olaparib can help control metastatic breast cancer in patients whose tumors have specific mutations in DNA repair genes. The pill works by blocking a protein that helps cancer cells fix their DNA, which may cause the cancer cells to die. Researchers are enrolling 114 patients with advanced breast cancer that has spread and who have not had more than two prior chemotherapy treatments for their metastatic disease.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC BREAST CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02115, United States
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
-
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
-
Duke University
Durham, North Carolina, 27708, United States
-
Indiana University
Indianapolis, Indiana, 46202, United States
-
Johns Hopkins University
Baltimore, Maryland, 21218, United States
-
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
-
Memorial Sloan Kettering Cancer Center Basking Ridge
Basking Ridge, New Jersey, 07920, United States
-
Memorial Sloan Kettering Cancer Center Bergen
Montvale, New Jersey, 07645, United States
-
Memorial Sloan Kettering Cancer Center Commack
Commack, New York, 11725, United States
-
Memorial Sloan Kettering Cancer Center Monmouth
Middletown, New Jersey, 07748, United States
-
Memorial Sloan Kettering Cancer Center Nassau
Uniondale, New York, 11553, United States
-
Memorial Sloan Kettering Cancer Center Westchester
East White Plains, New York, 10604, United States
-
UPMC Hillman Cancer Center - Erie
Erie, Pennsylvania, 16505, United States
-
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
-
University of California, San Francisco
San Francisco, California, 94143, United States
-
University of Chicago
Chicago, Illinois, 60637, United States
-
University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
-
University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
-
University of Washington Fred Hutchinson Cancer Care
Seattle, Washington, 98109, United States
Conditions
Explore the condition pages connected to this study.