Can a common drug help cancer patients regain appetite?
NCT ID NCT05705492
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times
Summary
This study tests whether olanzapine, a drug already used for other conditions, can help cancer patients who are losing weight and appetite. About 66 adults with advanced lung, stomach, or bowel cancers will receive either olanzapine or a placebo. The goal is to see if olanzapine leads to meaningful weight gain and better quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Olanzapine
- What this could lead to
- If it works, this could offer a way to help cancer patients gain weight and improve their appetite and quality of life.
- What could go wrong
- This is a small, early-phase trial, so results may not apply to everyone. Olanzapine can cause side effects like drowsiness and weight gain from other causes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
OHSU Knight Cancer Institute
RECRUITINGPortland, Oregon, 97239, United States
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