LOCALLY ADVANCED COLORECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED COLORECTAL CARCINOMA explained in plain language.
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New combo drug trial hopes to shrink tough cancers
Disease control Recruiting nowThis early-stage study tests a new combination of two drugs (trifluridine/tipiracil and talazoparib) in people with advanced colorectal or gastroesophageal cancers that have spread. The main goals are to find the safest dose and understand side effects. About 45 participants will…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Glow-in-the-dark surgery targets hidden cancer cells in colorectal patients
Disease control Recruiting nowThis study tests a two-step approach for people with advanced or returning colorectal cancer. First, a special drug makes cancer cells glow during surgery, helping surgeons remove more of them. Then, a laser activates the drug to kill any remaining cancer cells. The goal is to im…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Immune-boosting combo may shrink colorectal tumors before surgery
Disease control Recruiting nowThis study tests whether adding immune checkpoint inhibitors to standard chemotherapy before surgery can better shrink or eliminate tumors in people with locally advanced colorectal cancer. About 170 adults aged 18 to 75 with stage II/III colorectal cancer will be randomly assign…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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Could a common drug fight cancer wasting?
Symptom relief Recruiting nowThis study tests if olanzapine, a drug that affects brain chemicals, can help cancer patients who have lost their appetite and weight. The trial includes 66 adults with advanced lung, stomach, or colorectal cancers who are not being treated with a goal to cure. Participants will …
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC