LOCALLY ADVANCED COLORECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED COLORECTAL CARCINOMA explained in plain language.
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Glow-and-Kill surgery: new light therapy targets hidden cancer cells
Disease control Recruiting nowThis study tests a two-step approach during surgery for people with advanced or returning colorectal cancer. First, a drug makes cancer cells glow under blue light so surgeons can see and remove them. Then, red laser light activates the drug to kill any remaining cancer cells. Th…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New drug combo targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-phase study tests a combination of two drugs—trifluridine/tipiracil (a chemotherapy) and talazoparib (a targeted therapy)—in people with advanced colorectal or gastroesophageal cancers that have spread. The main goals are to find the safest dose and understand side eff…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Immunotherapy combo shows promise in colorectal cancer fight
Disease control Recruiting nowThis phase 2 trial tests whether adding an immune checkpoint inhibitor (a type of immunotherapy) to standard chemotherapy before surgery can improve outcomes for people with locally advanced colorectal cancer. About 170 participants will be randomly assigned to receive either the…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can a common drug help cancer patients regain appetite?
Symptom relief Recruiting nowThis study tests whether olanzapine, a drug already used for other conditions, can help cancer patients who are losing weight and appetite. About 66 adults with advanced lung, stomach, or bowel cancers will receive either olanzapine or a placebo. The goal is to see if olanzapine …
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC