Brain scans reveal how OCD therapy rewires the mind
NCT ID NCT01331876
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at how two different types of cognitive behavioral therapy (CBT) affect brain activity in people with obsessive-compulsive disorder (OCD). Thirty-five adults with OCD completed 15 therapy sessions and had brain scans before, during, and after treatment. The goal was to see if the therapies cause different changes in brain regions linked to OCD, such as the prefrontal cortex and basal ganglia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cognitive behavioral therapy
What this could lead to
If successful, this could help tailor OCD therapies based on brain activity changes, improving treatment effectiveness.
What could go wrong
This is a small, early-stage study (35 people) focused on brain imaging, not on proving which therapy works best. Results may not apply to all OCD patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Pitié-Salpêtrière hospital
Paris, 75013, France