New drug shows promise in preventing transplant complication

NCT ID NCT02867384

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether the drug obinutuzumab can prevent chronic graft-versus-host disease (cGVHD), a common and serious complication after a stem cell transplant. 181 people who had a stem cell transplant took part. The goal was to see if obinutuzumab could reduce the need for steroids to treat cGVHD in the first year after transplant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GRAFT VS HOST DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Stanford University

    Palo Alto, California, 94305, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.