New injection aims to smooth neck bands in phase 3 trial
NCT ID NCT07210463
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This phase 3 study tests whether NT 201 (incobotulinumtoxinA, a type of botulinum toxin) can safely reduce the appearance of moderate to severe neck bands (platysma prominence) compared to a placebo. About 300 adults in Europe will receive injections and be followed for several weeks. The main goal is to see if the bands improve by at least two grades on a five-point scale, as judged by both the doctor and the participant.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Merz Investigative Site
RECRUITINGLyon, 69006, France
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Merz Investigative Site
RECRUITINGMunich, Bavaria, 80539, Germany
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Merz Investigative Site
RECRUITINGBlankenfelde-Mahlow, Brandenburg, 15831, Germany
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Merz Investigative Site
RECRUITINGPotsdam, Brandenburg, 14467, Germany
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Merz Investigative Site
RECRUITINGFriedrichsdorf, Hesse, 61381, Germany
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Merz Investigative Site
RECRUITINGKassel, Hesse, 34117, Germany
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Merz Investigative Site
RECRUITINGBochum, North Rhine-Westphalia, 44793, Germany
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Merz Investigative Site
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40212, Germany
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Merz Investigative Site
RECRUITINGDrensteinfurt, 48317, Germany
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Merz Investigative Site
RECRUITINGHamburg, 20146, Germany
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Merz Investigative Site
RECRUITINGHamburg, 29354, Germany
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Merz Investigative Site
RECRUITINGWuppertal, 42287, Germany
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Merz Investigative Site
RECRUITINGKrakow, Lesser Poland Voivodeship, 30-002, Poland
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Merz Investigative Site
RECRUITINGOświęcim, Lesser Poland Voivodeship, 32-600, Poland
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Merz Investigative Site
RECRUITINGLublin, Lublin Voivodeship, 20-607, Poland
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Merz Investigative Site
RECRUITINGWarsaw, Masovian Voivodeship, 00-716, Poland
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Merz Investigative Site
RECRUITINGWarsaw, Masovian Voivodeship, 01-142, Poland
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Merz Investigative Site
RECRUITINGWarsaw, Masovian Voivodeship, 02-482, Poland
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Merz Investigative Site
RECRUITINGWarsaw, Masovian Voivodeship, 02-953, Poland
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Merz Investigative Site
RECRUITINGBialystok, Podlaskie Voivodeship, 15-453, Poland
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Merz Investigative Site
RECRUITINGGdynia, Pomeranian Voivodeship, 81-537, Poland
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Merz Investigative Site
RECRUITINGWarsaw, 02-962, Poland
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Merz Investigative Site
RECRUITINGLodz, Łódź Voivodeship, 90-436, Poland
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Merz Investigative Site
RECRUITINGOstrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland
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Merz Investigative Site
RECRUITINGPamplona, Navarre, 31008, Spain
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Merz Investigative Site
RECRUITINGValencia, 46010, Spain
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
IncobotulinumtoxinA (a type of botulinum toxin, also known as Xeomin or Bocouture)
What this could lead to
If it works, this could provide a safe and effective treatment to reduce the appearance of prominent neck bands, improving cosmetic concerns.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Results may vary, and there are risks like allergic reactions or temporary muscle weakness. The trial is still recruiting, so outcomes are not yet known.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.