PHYSIOLOGICAL EFFECTS OF DRUGS

This study is testing if an intravenous drug called Dimephosphon can help people recover better after a recent ischemic stroke. About 184 adults who had a stroke within the last 24-72 hours will receive either the drug or a placebo. Researchers will measure how well people recove…

This international study is testing whether using just one blood-thinning medication is as safe and effective as using two after a specific type of heart artery procedure. It focuses on patients aged 75 and older or those at high risk for bleeding. The goal is to find the best ba…

This study is testing whether a new, fast-acting drug called (2R,6R)-HNK can help people with major depression who haven't gotten better with standard treatments. Fifty participants will receive intravenous infusions of either the study drug or a placebo over several weeks to see…

This study is testing whether a sedative drug called dexmedetomidine can prevent long-term memory and thinking problems that sometimes occur after heart surgery. It will involve 2,400 patients aged 60 and older who are having planned heart surgery. Researchers will compare the dr…

This study is testing an injectable treatment called NT 201 for adults with moderate to severe neck bands. It will compare the treatment to a placebo (inactive) injection to see if it safely reduces the appearance of these bands. About 300 participants will be randomly assigned t…

This study is testing an injectable treatment to reduce the appearance of moderate to severe neck bands, often called 'platysmal bands.' It will involve 300 adults in the US who will receive either the active treatment or a placebo. The main goal is to see if the treatment is saf…

This study aims to understand how people with depression or bipolar disorder respond to their regular treatments. Researchers will observe 500 adults already receiving care, tracking their symptoms weekly for about 12 weeks. The goal is to find patterns that might help predict wh…