Could a ketamine mist lift severe depression fast?

NCT ID NCT06752759

First seen May 02, 2026 · Last updated Jun 11, 2026 · Updated 10 times

Summary

This study tests whether inhaling ketamine through a nebulizer can quickly reduce symptoms of moderate to severe depression in hospitalized adults. About 40 participants will receive either ketamine or a placebo (midazolam) and be monitored for changes in depression scores over 8-10 days. The goal is to see if this approach offers a fast-acting treatment option for those in need.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Maimonides Medical Center

    RECRUITING

    Brooklyn, New York, 11219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.