Could a ketamine mist lift severe depression fast?

NCT ID NCT06752759

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether inhaling ketamine through a nebulizer can quickly reduce symptoms of moderate to severe depression in hospitalized adults. About 40 participants will receive either ketamine or a placebo (midazolam) and be monitored for changes in depression scores over 8-10 days. The goal is to see if this approach offers a fast-acting treatment option for those in need.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Maimonides Medical Center

    RECRUITING

    Brooklyn, New York, 11219, United States

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