New injection could smooth neck bands in phase 3 trial
NCT ID NCT07122193
First seen Sep 30, 2025 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This phase 3 trial tests whether NT 201 (incobotulinumtoxinA, a botulinum toxin type A injection) can safely reduce the appearance of moderate to severe neck bands (platysma prominence) compared to a placebo. About 300 adults in the US are participating in this double-blind study. The main goal is to see if the treatment improves neck band appearance by at least two grades on a five-point scale at two weeks after injection.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Merz Investigative Site
Scottsdale, Arizona, 85260, United States
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Merz Investigative Site
Encino, California, 91436, United States
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Merz Investigative Site
Los Angeles, California, 90069, United States
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Merz Investigative Site
Redondo Beach, California, 90277, United States
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Merz Investigative Site
Santa Monica, California, 90404, United States
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Merz Investigative Site
Vista, California, 92803, United States
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Merz Investigative Site
Greenwood Village, Colorado, 80111, United States
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Merz Investigative Site
Westport, Connecticut, 06880, United States
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Merz Investigative Site
Washington D.C., District of Columbia, 20037, United States
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Merz Investigative Site
Aventura, Florida, 33180, United States
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Merz Investigative Site
Boca Raton, Florida, 33431, United States
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Merz Investigative Site
Bradenton, Florida, 34209, United States
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Merz Investigative Site
Coral Gables, Florida, 33143, United States
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Merz Investigative Site
Coral Gables, Florida, 33146, United States
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Merz Investigative Site
West Palm Beach, Florida, 33404, United States
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Merz Investigative Site
Alpharetta, Georgia, 30005, United States
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Merz Investigative Site
Naperville, Illinois, 60563, United States
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Merz Investigative Site
Hunt Valley, Maryland, 21030, United States
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Merz Investigative Site
Mount Kisco, New York, 10549, United States
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Merz Investigative Site
New York, New York, 10021, United States
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Merz Investigative Site
New York, New York, 10028, United States
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Merz Investigative Site
Chapel Hill, North Carolina, 27517, United States
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Merz Investigative Site
Wilmington, North Carolina, 28405, United States
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Merz Investigative Site
Ardmore, Pennsylvania, 19003, United States
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Merz Investigative Site
Nashville, Tennessee, 37215, United States
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Merz Investigative Site
Dallas, Texas, 75225, United States
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Merz Investigative Site
Arlington, Virginia, 22209, United States
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Merz Investigative Site
San Juan, 00917, Puerto Rico
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
incobotulinumtoxinA (a botulinum toxin type A injection, also known as Xeomin)
What this could lead to
If it works, this could provide a safe and effective treatment to reduce the appearance of neck bands (platysma prominence) in adults.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Results may vary, and there are risks like allergic reactions or temporary muscle weakness. The trial is still ongoing, so final results are not yet available.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.