New injection could smooth neck bands in phase 3 trial

NCT ID NCT07122193

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether NT 201 (incobotulinumtoxinA, a botulinum toxin type A injection) can safely reduce the appearance of moderate to severe neck bands (platysma prominence) compared to a placebo. About 300 adults in the US are participating in this double-blind study. The main goal is to see if the treatment improves neck band appearance by at least two grades on a five-point scale at two weeks after injection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
incobotulinumtoxinA (a botulinum toxin type A injection, also known as Xeomin)
What this could lead to
If it works, this could provide a safe and effective treatment to reduce the appearance of neck bands (platysma prominence) in adults.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Results may vary, and there are risks like allergic reactions or temporary muscle weakness. The trial is still ongoing, so final results are not yet available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Merz Investigative Site

    Scottsdale, Arizona, 85260, United States

  • Merz Investigative Site

    Encino, California, 91436, United States

  • Merz Investigative Site

    Los Angeles, California, 90069, United States

  • Merz Investigative Site

    Redondo Beach, California, 90277, United States

  • Merz Investigative Site

    Santa Monica, California, 90404, United States

  • Merz Investigative Site

    Vista, California, 92803, United States

  • Merz Investigative Site

    Greenwood Village, Colorado, 80111, United States

  • Merz Investigative Site

    Westport, Connecticut, 06880, United States

  • Merz Investigative Site

    Washington D.C., District of Columbia, 20037, United States

  • Merz Investigative Site

    Aventura, Florida, 33180, United States

  • Merz Investigative Site

    Boca Raton, Florida, 33431, United States

  • Merz Investigative Site

    Bradenton, Florida, 34209, United States

  • Merz Investigative Site

    Coral Gables, Florida, 33143, United States

  • Merz Investigative Site

    Coral Gables, Florida, 33146, United States

  • Merz Investigative Site

    West Palm Beach, Florida, 33404, United States

  • Merz Investigative Site

    Alpharetta, Georgia, 30005, United States

  • Merz Investigative Site

    Naperville, Illinois, 60563, United States

  • Merz Investigative Site

    Hunt Valley, Maryland, 21030, United States

  • Merz Investigative Site

    Mount Kisco, New York, 10549, United States

  • Merz Investigative Site

    New York, New York, 10021, United States

  • Merz Investigative Site

    New York, New York, 10028, United States

  • Merz Investigative Site

    Chapel Hill, North Carolina, 27517, United States

  • Merz Investigative Site

    Wilmington, North Carolina, 28405, United States

  • Merz Investigative Site

    Ardmore, Pennsylvania, 19003, United States

  • Merz Investigative Site

    Nashville, Tennessee, 37215, United States

  • Merz Investigative Site

    Dallas, Texas, 75225, United States

  • Merz Investigative Site

    Arlington, Virginia, 22209, United States

  • Merz Investigative Site

    San Juan, 00917, Puerto Rico

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