Stem cells armed with virus take on deadly brain tumors

NCT ID NCT05139056

Terminated Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This early-stage trial tests the safety of giving multiple doses of neural stem cells that carry a cancer-killing virus directly into the brain of people with recurrent glioblastoma, a severe brain cancer. The stem cells are designed to seek out tumor cells and release the virus to destroy them. The study involves 36 adults whose cancer has returned after initial treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

City of Hope Medical Center

Duarte, California, 91010, United States
Northwestern University

Chicago, Illinois, 60611, United States
Standford University

Stanford, California, 94305, United States
Wake Forest University

Winston-Salem, North Carolina, 27109, United States

Conditions

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CURRENTLY ONLY ENROLLING GLIOBLASTOMA PATIENTS AT FIRST RECURRENCE CURRENTLY ONLY ENROLLING GLIOBLASTOMA PATIENTS AT FIRST RECURRENCE