Stem cells armed with a virus take on deadly brain tumors

NCT ID NCT05139056

Terminated Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new treatment for people with glioblastoma, an aggressive brain cancer that has come back. The therapy uses special neural stem cells that can find cancer cells in the brain and release a virus that kills them. The main goal is to check the safety of giving multiple doses directly into the brain, and to see if it helps control the disease.

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Conditions

The condition(s) this trial relates to.

glioblastoma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CURRENTLY ONLY ENROLLING GLIOBLASTOMA PATIENTS AT FIRST RECURRENCE

Contacts and locations

Locations

City of Hope Medical Center

Duarte, California, 91010, United States
Northwestern University

Chicago, Illinois, 60611, United States
Standford University

Stanford, California, 94305, United States
Wake Forest University

Winston-Salem, North Carolina, 27109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.