Synthetic skin patch could revolutionize burn treatment

NCT ID NCT04090424

Ongoing Disease control Sponsor: PolyNovo Biomaterials Pty Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new synthetic skin substitute called NovoSorb BTM for treating severe burns. About 150 adults with deep burns covering 3% to 60% of their body will receive either the new matrix or standard care. The goal is to see if the new material helps burns close completely after skin grafting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NovoSorb Biodegradable Temporizing Matrix (BTM) - a synthetic skin substitute
What this could lead to: If successful, this could provide a new, effective option for treating severe burns, potentially improving healing and reducing complications.
What could go wrong: This is a single study with 150 participants, and results may not apply to all burn patients. The device is synthetic and may not integrate as well as natural tissue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

burn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BURNS

Contacts and locations

Locations

Akron Children's Hospital, Burn Center

Akron, Ohio, 44308, United States
Bembde Hospital

Aurangabad, Maharashtra, India
Bridgeport Hospital

Bridgeport, Connecticut, 06610, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Emory University at Grady Memorial Hospital

Atlanta, Georgia, 30303, United States
Ganga Medical Centre and Hospitals PVT Ltd

Coimbatore, Tamil Nadu, India
Lehigh Valley Hospital and Health Network

Allentown, Pennsylvania, 18103, United States
Loyola University of Chicago

Maywood, Illinois, 60153, United States
Massachusetts General Hospital

Boston, Massachusetts, 02446, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
National Burns Centre

Mumbai, Maharashtra, India
New York Presbyterian Weill Cornell Medicine

New York, New York, 10065, United States
Southern California Regional Burn Center at LAC+USC

Los Angeles, California, 90033, United States
Tampa General Hospital

Tampa, Florida, 33606, United States
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
The Ohio State University/ Wexner Medical Center

Columbus, Ohio, 43210, United States
UW Health University Hospital

Madison, Wisconsin, 53792, United States
University Medical Center, New Orleans

New Orleans, Louisiana, 70112, United States
University of California Davis Medical Center

Sacramento, California, 95817, United States
University of Iowa Hospital and Clinics

Iowa City, Iowa, 52242, United States
University of Kansas Hospital

Kansas City, Kansas, 66160, United States
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
Valleywise Health

Phoenix, Arizona, 85008, United States
Virginia Commonwealth University Medical Center

Richmond, Virginia, 23219, United States
Wake Forest Baptist Health

Winston-Salem, North Carolina, 24157, United States

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