Study tests if safer painkillers can replace opioids for Kids' broken elbows

NCT ID NCT06187584

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether nonopioid pain relievers (acetaminophen and ibuprofen) work as well as opioids (hydrocodone/acetaminophen) for children after surgery for a severe elbow fracture. 137 children aged 4 to 10 were randomly assigned to one of the two pain regimens. Their pain levels were tracked for five days after surgery, and parents rated their satisfaction with pain control. The goal is to find a safer, effective standard for managing pain after this common childhood injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hydrocodone/acetaminophen, acetaminophen, ibuprofen

What this could lead to

If successful, this could show that nonopioid pain relievers work just as well as opioids for children after this type of elbow surgery, reducing the need for stronger, riskier medications.

What could go wrong

This is a single completed study with 137 children, so results may not apply to all patients or fracture types. Pain is subjective, and individual responses vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

humerus fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Mercy Hospital & Clinics

    Kansas City, Missouri, 64108, United States