New embryo test could boost IVF success without poking the embryo
NCT ID NCT04000152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new, non-invasive way to check embryos for chromosome problems before IVF. Instead of taking a cell from the embryo, doctors analyzed the fluid the embryo grew in. The goal was to see if this method could help choose the embryo most likely to lead to a healthy pregnancy. The trial involved 296 patients but was stopped early, so we don't have final answers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
non-invasive preimplantation genetic testing for aneuploidy (niPGT-A) via spent blastocyst media analysis
What this could lead to
If successful, this could offer a cheaper, safer way to choose the healthiest embryo for IVF without harming it.
What could go wrong
The trial was terminated early, so results are limited. The test may not be accurate enough to replace current methods, and its benefit on pregnancy rates is unproven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centro Procreazione Assistita DEMETRA
Florence, Firenze, 50141, Italy
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Crecer: Centro de Reproducción y Genética Humana
Mar del Plata, Buenos Aires, Argentina
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Hospital Ruber Internacional
Madrid, Madrid, 28035, Spain
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Hôpital Foch
Suresnes, Suresnes, 92150, France
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Nilo Frantz - Centro de Reprodução Humana
Boa Vista, Porto Alegre, 91330-002, Brazil
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Saresa - Reproducción Humana Asistida
Salta, Salta Province, 4400, Argentina
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Società Italiana Studi di Medicina della Riproduzione (S.I.S.M.e.R.)
Bologna, Bologna, 40138, Italy
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Vida - Centro de Fertilidade
Rio de Janeiro, Rio de Janeiro, 22793-080, Brazil