New male birth control pill could work in minutes
NCT ID NCT07393334
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new non-hormonal male contraceptive called NLS-133, taken just before sex to reduce sperm count and semen volume. Ten healthy men will receive the drug, an active control, or a placebo in random order. The goal is to see if it safely and effectively lowers sperm count and motility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NLS-133 (combination of two FDA-approved drugs)
What this could lead to
If it works, this could lead to a new non-hormonal, on-demand male contraceptive pill.
What could go wrong
This is a very small early-phase trial with only 10 men, so results may not apply widely. The drug is taken just before sex, so effectiveness and safety are still uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Population Center for Research in Human Reproduction and Departments of Medicine, University of Washington
RECRUITINGSeattle, Washington, 98195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••