Hydrogel implant could offer reversible male contraception

NCT ID NCT05134428

Completed Disease control Sponsor: Contraline, Inc Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new device called the ADAM System, a hydrogel implant placed in the sperm-carrying tubes to block sperm. It was tested in 25 healthy men to see if it is safe and works as a non-permanent form of male birth control. The implant is designed to be reversible, unlike a standard vasectomy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hydrogel implant (ADAM System)
What this could lead to: If successful, this could provide a long-lasting but reversible male contraceptive option, similar to a vasectomy but without permanent effects.
What could go wrong: This is a small, early feasibility study with only 25 men. The implant may not reliably block sperm, could cause side effects, or may not be easily reversible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY MALE ADULTS MALE CONTRACEPTION

Contacts and locations

Locations

AndroUrology

Brisbane, Queensland, 4001, Australia
Epworth HealthCare

East Melbourne, Victoria, 3002, Australia
South Coast Urology

Wollongong, New South Wales, 2500, Australia

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