Immunotherapy combo tested for rare kidney cancer, but trial stopped early

NCT ID NCT03274258

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tested two immunotherapy drugs, nivolumab and ipilimumab, in 10 people with a rare and aggressive kidney cancer called renal medullary carcinoma. The goal was to see if the drugs could shrink tumors or slow cancer growth. However, the study was terminated early, so the results are limited and it is unclear how well the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nivolumab and ipilimumab (immunotherapy drugs)

What this could lead to

If it works, this could point toward a treatment option for a rare and aggressive kidney cancer.

What could go wrong

The trial was terminated early with only 10 participants, so results are very limited. Immunotherapy can cause serious side effects like organ inflammation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

collecting duct carcinoma kidney medullary carcinoma renal cell adenocarcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States