Immunotherapy before surgery shrinks lung tumors in Early-Stage trial

NCT ID NCT03158129

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested giving immunotherapy drugs (nivolumab alone or with ipilimumab) or immunotherapy plus chemotherapy before surgery for people with early-stage non-small cell lung cancer (stages I to IIIA). The goal was to see if these treatments could shrink or eliminate the tumor before surgical removal. The trial enrolled 101 participants and measured how many had a major or complete response in the tumor tissue after treatment.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States