Immunotherapy before surgery shrinks lung tumors in Early-Stage patients

NCT ID NCT03158129

First seen May 12, 2026 · Last updated May 16, 2026 · Updated 3 times

Summary

This study tested giving immunotherapy drugs (nivolumab alone or with ipilimumab or chemotherapy) before surgery to people with early-stage non-small cell lung cancer. The goal was to see if these treatments could shrink tumors and improve outcomes. About 101 patients took part, and the results showed that many had a major reduction in tumor cells, with some having no cancer left at the time of surgery.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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