Promising drug combo targets tough breast cancer after surgery

NCT ID NCT03945721

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 24 times

Summary

This early-phase study tests the drug niraparib given together with radiation therapy after surgery for triple negative breast cancer. It includes 21 patients who still had cancer cells after chemotherapy. The main goal is to find the safest dose of niraparib and see if the combination helps prevent the cancer from coming back.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute/Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.