Cancer drug combo studied in kids – but trial stopped early

NCT ID NCT04544995

First seen Jan 21, 2026 · Last updated Jun 16, 2026 · Updated 21 times

Summary

This early-stage study tested a combination of two drugs (niraparib and dostarlimab) in children and teens aged 6 months to 18 years whose solid tumors had come back or did not respond to treatment. The main goals were to find safe doses and see how the drugs worked in the body. The study was terminated, so results are limited.

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Contacts and locations

Locations

  • GSK Investigational Site

    Birmingham, B4 6NH, United Kingdom

  • GSK Investigational Site

    Sutton, SM2 5PT, United Kingdom

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.