Cancer drug combo trial for kids halted early

NCT ID NCT04544995

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a combination of two drugs, niraparib and dostarlimab, in children and teens (ages 6 months to 17 years) with solid tumors that had come back or were not responding to treatment. The goal was to find a safe dose and see if the drugs could shrink tumors. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Birmingham, B4 6NH, United Kingdom

  • GSK Investigational Site

    Sutton, SM2 5PT, United Kingdom

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Other studies related to the condition(s) this trial covers.