Nicotine pouches tested as cigarette alternative

NCT ID NCT07476144

Recruiting now Knowledge-focused Sponsor: JT International SA Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how nicotine pouches affect the body and cravings in adult smokers. About 55 healthy smokers will try nine different nicotine pouches, cigarettes, nicotine gum, and a comparator pouch. Researchers will measure nicotine levels in the blood, heart rate, blood pressure, and how much participants like each product. The goal is to understand if these pouches could be a less harmful option for smokers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nicotine pouch
What this could lead to: If successful, this could provide data to support safer nicotine alternatives for smokers who cannot quit.
What could go wrong: This is an early-phase study with only 55 participants, so results may not apply to everyone. It measures short-term effects, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING BEHAVIORS

Contacts and locations

Locations

AMR
RECRUITING

Knoxville, Tennessee, 37920, United States
ICON San Antonio
RECRUITING

San Antonio, Texas, 78209, United States

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