Nicotine pouches tested as cigarette alternative
NCT ID NCT07476144
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how nicotine pouches affect the body and cravings in adult smokers. About 55 healthy smokers will try nine different nicotine pouches, cigarettes, nicotine gum, and a comparator pouch. Researchers will measure nicotine levels in the blood, heart rate, blood pressure, and how much participants like each product. The goal is to understand if these pouches could be a less harmful option for smokers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nicotine pouch
What this could lead to
If successful, this could provide data to support safer nicotine alternatives for smokers who cannot quit.
What could go wrong
This is an early-phase study with only 55 participants, so results may not apply to everyone. It measures short-term effects, not long-term health outcomes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AMR
RECRUITINGKnoxville, Tennessee, 37920, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ICON San Antonio
RECRUITINGSan Antonio, Texas, 78209, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••